Chairs & Organizing Committee
Chairs
David Geffen School of Medicine at UCLA
Ronald Reagan UCLA Medical Center
Dr. Jahr has been at the forefront the conduct of definitive preclinical and clinical studies involving the application of Hemoglobin-based Oxygen Carriers in the treatment of hemorrhage and orthopedic surgery. He is the world’s foremost expert in the use of advanced diagnostic techniques in the study of the impact of volumizing fluids and HBOCs on coagulapathy, and related coagulation and platelet function. Throughout his extraordinary professional career, Dr. Jahr has been interested in the use of resuscitative fluids, blood transfusions, and intervention in the treatment of severe trauma, and the clinical efficacy of the use of blood substitutes, including perfluorocarbon technologies and hemoglobin based oxygen carriers to reduce the need for blood transfusions in clinical practice. He has served as co-editor of two recent highly acclaimed textbooks on blood substitutes (Nanobiotherapeutic Based Blood Substitutes [Regenerative Medicine, Artificial Cells and Nanomedicine-Vol 6], Edited by TMS Chang, L Bulow, JS Jahr, H Sakai, CM Yang. World Science Publisher, December 2021. ISBN: 978-981-122-868-1 https://doi.org/10.1142/12054. Blood Substitutes and Oxygen Biotherapeutics, Edited by Liu H, Kaye AD, Jahr JS. Springer Publishing 2022. ISBN-13: 97-3030959746; ISBN-10: 3030959740) and has been the principal investigator in over 30 clinical trials, has published over 250 studies, abstracts, review articles, book chapters, and case studies. Additionally, he has studied acute pain and has co-edited a text, titled: The Essence of Analgesia and Analgesics and has authored multiple studies, reviews and chapters on the topic of minimizing opioid use for pain and multimodal analgesia, including three on iv meloxicam recently. He has served on the editorial review boards and/or reviewer for Anesthesiology Review, American Journal of Anesthesiology, American Journal of Therapeutics, Journal of Cardiovascular Pharmacology and Therapeutics, Journal of Clinical Anesthesiology, Critical Care Medicine, American Journal of Physiology: Heart and Circulatory Physiology, Hematological, Anesthesiology, British Journal of Anesthesiology, and Vascular Pharmacology, and regularly lectures on issues regarding acute pain management, anesthesiology, oxygen therapeutics, and the management of blood products in surgical operations.
Director, Center of Blood Oxygen Transport and Hemostasis
CSO and Founding Partner, KaloCyte
Allan Doctor, MD is Professor of Pediatrics and Bioengineering at the University of Maryland School of Medicine, where he directs the Center for Blood Oxygen Transport and Hemostasis. He is a Pediatric Intensivist and previously led Pediatric Critical Care at Washington University and St Louis Children’s Hospital for 10 years, stepping down and then transitioning to UMB to focus on a rapidly expanding research program and on development of a novel bio-synthetic artificial red cell. His laboratory studies the role of red blood cell-based signaling in the control of regional blood flow, related pathophysiology arising from acquired red cell injuries, blood substitute design, and on translational transfusion medicine in critical illness.
Co-Chairs
Scientific Director of Cellular Therapies
Dr. Pati is a vascular biologist and is currently at employed at the University of California San Francisco. She is the Scientific Director of Cellular Therapies and Professor in the Department of Laboratory Medicine. She is by training a cancer vascular biologist with an interest in the role of endothelial dysfunction and vascular compromise in the pathogenesis of human disease. Dr. Pati is internationally recognized for her work on endothelial dysfunction and resuscitation in trauma. Dr. Pati received her A.B. in Molecular Biology from Princeton University and her MD. PhD. from the University of Maryland. She completed a post-doctoral fellowship in Neuroscience at the Baylor College of Medicine and the University of Texas in Houston. Following her fellowship, Dr. Pati’s specific areas of investigation involve the use of stem cells, blood products and novel resuscitative modalities that can mitigate endothelial dysfunction, inflammation and coagulation disturbances found in hemorrhage and traumatic injury. Her lab aims to specifically understand the mechanisms of vascular compromise in injury and novel methods by which to modulate it. Her lab is funded by the DOD, NIH and private industry. Recent studies by Dr. Pati have involved the therapeutic potential and mechanisms of action of novel blood products in mitigating organ injury after hemorrhagic shock and trauma and TBI.
Case Western University, Biomedical Engineering
Dr. Anirban Sen Gupta received a double major in Chemistry (B.Sc. HONORS) and Chemical Engineering (B. Tech.) from the University of Calcutta (Kolkata), West Bengal, India for his undergraduate training, and received MS and PhD in Chemical Engineering with polymeric biomaterials focus from the University of Akron, Ohio, USA under the guidance and mentorship of Dr. Stephanie Lopina. He also underwent valuable industrial experience at Guilford Pharmaceuticals (Baltimore, Maryland) and Procter & Gamble (Cincinnati, Ohio), as well as post-doctoral training in Biomedical Engineering at Case Western Reserve University under the mentorship of Dr. Roger Marchant. Dr. Sen Gupta started his faculty position as an Assistant Professor in the Department of Biomedical Engineering at Case Western in 2006 and was tenured to Full Professor in 2017. Dr. Sen Gupta was awarded the Leonard Case Jr. endowed professorship at Case School of Engineering in 2021. Dr. Sen Gupta is a Fellow of American Institute for Medical and Biological Engineering (AIMBE). Dr. Sen Gupta serves as a member of the International Editorial Board of the journal Biomaterials (Elsevier) and an Associate Editor for Journal of Thrombosis and Haemostasis (formerly Wiley, now Elsevier). Dr. Sen Gupta also serves on the Working Group on Hemostasis and Thrombosis for American Society of Hematology. Dr. Sen Gupta’s current research involves collaborations across Engineering and Medicine at Case Western, several other universities within the US, as well as international collaborations with Forschungszentrum Jülich (Germany), University of Birmingham (UK) and INSERM (Paris). He has also co-founded a biotech startup, Haima Therapeutics, with a vision for translation and commercialization of technologies developed in his laboratory. The ongoing research endeavors in Sen Gupta laboratory are supported by funding from NSF, NIH, DoD, State of Ohio and Case-Coulter Translational Research Partnership. Dr. Sen Gupta is dedicated and deeply committed to providing inclusive and equitable mentorship to a diverse group of trainees and researchers in his laboratory.
Professor, Chemical and Biomolecular Engineering
The Ohio State University College of Engineering
Professor Palmer is a global leader in blood substitute research, and engineering biomaterials for use in transfusion medicine and tissue engineering. He is currently working to develop safer, more commercially viable red blood cell substitutes that could tide patients over until they receive a blood transfusion.
Professor Palmer’s research interests encompass the development of novel hemoglobin-based oxygen carriers for a variety of applications in transfusion medicine and tissue engineering. His lab is also developing therapeutics for the detoxification of hemoglobin/heme/iron, non-heme based plasma substitutes, and monocyte/macrophage targeted drug delivery systems. He is author of more than 170 peer reviewed publications. Among others, he received the National Science Foundation Career Award, and the Harrison Faculty Award for Excellence in Engineering Education from The Ohio State University College of Engineering. Prof. Palmer currently serves on the International Scientific Advisory Committee on Blood Substitutes, and is a member of the Bioengineering, Technology, and Surgical Sciences Study Section at the National Institutes of Health. In 2015, he was inducted into the College of Fellows of the American Institute for Medical and Biological Engineering. Palmer’s research is supported by grants from the National Institutes of Health and the Department of Defense.
Conference Management
Etcetera Events & Promotions, Inc.
Contact for any information regarding the ISBS conference, registration & sponsorship
Sue Anderson – [email protected]
Liz Pearce – [email protected]
